Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity.

نویسندگان

  • Changjiang Yang
  • Juanjuan Li
  • Rong Zhou
  • Xiangyu Chen
  • Yunpeng Gao
  • Zhengjie He
چکیده

Novel spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines have been synthesized in good to excellent yields via the annulation reactions of the corresponding 3-alkylideneoxindoles and 3-alkylidenebenzofuranones with Huisgen zwitterions. The preliminary bioassay demonstrated that some of the spiropyrazolines possess good in vitro fungicidal activity against several crop fungi at a concentration of 50 μg mL(-1).

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منابع مشابه

PYRAZOLINES AND ISOXAZOLINES (I). SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF P-(1-ACYL-3-METHYL-5-ARYL-4 PYRAZOLINOYL / P-(3-METHYL-5-ARYL-4ISOXAZOLINOYL) ARSANILIC ACID

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 17  شماره 

صفحات  -

تاریخ انتشار 2015